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Important Scientific Articles Regarding Heart Disease

The following links are to some very important scientific articles regarding heart disease, L-arginine, vitamine D, and medical breakthroughs resulting from increased knowledge of nitric oxide and its cardiovascular benefits. Additional articles of interest have been included which may not be directly related to cardiovascular disease, but provide insight into recent scientific discoveries.


Scientific Articles Regarding L-Arginine

L-Arginine: A Primer for Its Power
Dr. J. Joseph Prendergast
Founder, Medical Director, Endocrine Metabolic Medical Center

Human Clinical Study on Heart Disease
The High Desert Heart Institute (HDHI)

Nobel Prize Winner’s Breakthrough – Prevent Heart Attack and Stroke with Nitric Oxide
Louis J. Ignarro, PhD
University of California at Los Angeles, School of Medicine

The Pharmacodynamics of L-Arginine
Rainer H. Böger*
Clinical Pharmacology Unit, Institute of Experimental and Clinical Pharmacology, University Hospital Hamburg-Eppendorf, Germany

L-Arginine, the substrate for NO synthesis: an alternative treatment for premature atherosclerosis?
Siasos G, Tousoulis D, Antoniades C, Stefanadi E, Stefanadis C.
Cardiology Unit, Hippokration Hospital, Athens University Medical School, S. Karagiorga 69, Glifada, 16 675, Athens, Greece.

l-arginine availability regulates T-lymphocyte cell-cycle progression
Paulo C. Rodriguez, David G. Quiceno, and Augusto C. Ochoa
Tumor Immunology Program, Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA; Department of Pediatrics, Louisiana State University, Health Sciences Center, New Orleans, LA

L-citrulline and L-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits
Toshio Hayashi,*† Packiasamy A. R. Juliet,* Hisako Matsui-Hirai,* Asaka Miyazaki,* Akiko Fukatsu,* Jun Funami,* Akihisa Iguchi,* and Louis J. Ignarro‡§†
*Department of Geriatrics, Nagoya University Graduate School of Medicine,Japan; and ‡Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles

L-Arginine Rebuttal, Monday, March 20, 2006
Response to JAMA 1/4/06 Vol 295, No.1, 58-64, L-arginine therapy in Acute Myocardial Infarction Dr. Joe's E-News - A Diabetes Newsletter,
Dr. Joe Prendergast, Owner and Medical Director of Endocrine Metabolic Medical Center, writes this weekly e-newsletter about diabetes, its complications and related issues. This is his rebuttal to the scientific article written about the Johns Hopkins University study where it was reported in JAMA and by many other sources that L-arginine should not be taken if you've had a heart attack.

Scientific Articles Regarding Benefits of L-Arginine and Nitric Oxide for Exercise Capacity

L-Arginine Supplementation May Benefit Heart Transplant Patients
Doutreleau S, Rouyer O, Di Marco P, et al.
The American Journal of Clinical Nutrition, May 2010

L-Arginine - The Key to Nitric Oxide (NO) Supplements...But What Does it Do?
BodyBuilding.com, 2010 Studies and Research Blog

Scientific Articles Regarding Vitamin D

Millions of Needless Deaths
by William Faloon
Director of the Life Extension Foundation

Why Governments Are Selling Vitamin D Short
By Sam Apple

Lack of vitamin D may increase heart disease risk
Michael J. Pencina, Ph.D.; Sarah L. Booth, Ph.D.; Paul F. Jacques, D.Sc.; Erik Ingelsson, M.D., Ph.D.; Katherine Lanier, B.S.; Emelia J. Benjamin, M.D.; Ralph B. D'Agostino, Ph.D.; Myles Wolf, M.D.; and Ramachandran S. Vasan, M.D.
Framingham Heart Study, funded by The National Institute of Health, U.S. Department of Agriculture and American Heart Association.

Too Little Vitamin D Puts Heart at Risk
Research Suggests Vitamin D Deficiency May Be an Unrecognized Heart Disease Risk Factor
By Jennifer Warner,
WebMD Health News, Reviewed by Elizabeth Klodas, MD, FACC

New Model Of Cancer Development:
Low Vitamin D Levels May Have Role

ScienceDaily (May 26, 2009) - In studying the preventive effects of vitamin D, researchers at the Moores Cancer Center at the University of California, San Diego, have proposed a new model of cancer development that hinges on a loss of cancer cells' ability to stick together.
by Cedric Garland, Edward D. Gorham, Sharif B. Mohr and Frank C. Garland, UC San Diego

Vitamin D Is The 'It' Nutrient Of The Moment
ScienceDaily (Jan. 14, 2009) — Vitamin D is quickly becoming the "it" nutrient with health benefits for diseases, including cancer, osteoporosis, heart disease and now diabetes.

Just One Pill Away
by Bill Sardi,
consumer advocate and health journalist, writing from San Dimas, California

Men With Vitamin D Deficiency May Have Increased Risk Of
Heart Attack

ScienceDaily (June 11, 2008) — Low levels of vitamin D appear to be associated with higher risk of myocardial infarction (heart attack) in men, according to a new report.

Vitamin D Halts Growth of Breast Cancer Tumors
by Mike Adams
NaturalNews Editor

Vitamin D Levels Linked to Breast-Cancer Prognosis
GrassrootsHealth, A Public Health Promotion Organization,
Reprinted from the ctv.ca website

Vitamin D Fights Crohn's Disease
Mercola.com - Take Control of Your Health, February 20, 2010

General Scientific Articles of Interest

Nutrition Trends of 2008

Resveratrol is "Nature's Medicine" for Cancer, Heart Disease and Much More
by Mike Adams
the Health Ranger, NaturalNews Editor

Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy
by Erick H. Turner, M.D., Annette M. Matthews, M.D., Eftihia Linardatos, B.S., Robert A. Tell, L.C.S.W., and Robert Rosenthal, Ph.D.

Another Blow to Magic Bullet Drugs: Statins Impair Brains
by Sherry Baker
Health Sciences Editor

900 Studies Show Statin Drugs are Dangerous
Mercola.com - Take Control of Your Health, February 21, 2009

Minding Your Blood Pressure Could Prevent Alzheimer's
Mercola.com - Take Control of Your Health, February 18, 2010


More scientific articles will be provided as they become available.

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